CD44 anticorps

N° du produit ABIN1106379

Cet anticorps anti-CD44 est un anticorps Souris Monoclonal détectant CD44 dans FACS, IP, Func et EIA. Adapté pour Humain.

Aperçu rapide pour CD44 anticorps (ABIN1106379)

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: B-F24

Détail du produit anti-CD44 anticorps

Specificité: Recognises the soluble Hyaluronate Cell Adhesion Molecule (H-CAM), a 85-250 kDa protein.

Purification: Ion Exchange Chromatography.

Stérilité: 0.22 μm filtered

Immunogène: U937 cell line

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free.

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

ID gène: 960

NCBI Accession: NP_000601

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling